Basic Information
| LncRNA/CircRNA Name | FAM3D-AS1 |
| Synonyms | NA |
| Region | GRCh38_3:58607080-58634440 |
| Ensemble | ENSG00000244383 |
| Refseq | NR_134853 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-PCR , Western blot , in vitro knockdown etc. |
| Sample | cell lines(HCT-116, SW116, SW480, SW620, and HT29) |
| Expression Pattern | up-regulated |
| Function Description | FAM3D-AS1 located in cytoplasm. Overexpression of FAM3D-AS1 significantly inhibited the cell proliferation, cell survival rates, and invaded cells.FAM3D-AS1 reversed the EMT process. FAM3D-AS1 inhibits CRC development through NF-?B signaling pathway. |
| Pubmed ID | 31147452 |
| Year | 2019 |
| Title | Long Noncoding RNA FAM3D-AS1 Inhibits Development of Colorectal Cancer Through NF-?B Signaling Pathway |
External Links
| Links for FAM3D-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |