Basic Information
| LncRNA/CircRNA Name | FAM83H-AS1 |
| Synonyms | NA |
| Region | GRCh38_8:123201172-123202743 |
| Ensemble | ENSG00000204949 |
| Refseq | NR_024479 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, Western blot |
| Sample | TNBC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | FAM83H-AS1 functions as an oncogenic lncRNA that regulates miR-136-5p and MTDH expression during TNBC progression, and suggest that targeting the FAM83H-AS1/miR-136-5p/MTDH axis may serve as a novel therapeutic target in TNBC. |
| Pubmed ID | 32074085 |
| Year | 2020 |
| Title | LncRNA FAM83H-AS1 promotes triple-negative breast cancer progression by regulating the miR-136-5p/metadherin axis |
External Links
| Links for FAM83H-AS1 | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |