Basic Information
| LncRNA/CircRNA Name | FAM83H-AS1 |
| Synonyms | NA |
| Region | GRCh38_8:123201172-123202743 |
| Ensemble | ENSG00000204949 |
| Refseq | NR_024479 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | CRC tissues, cell lines (HCT116, SW480, HT29 and SW620) |
| Expression Pattern | up-regulated |
| Function Description | Notably, the overexpression of FAM83H-AS1 and VPS9D1-AS1 indicated shorter OS time than lower expression. The overexpression of FAM83H-AS1 and VPS9D1-AS1 was validated in cancerous tissues. Thus, FAM83H-AS1 and VPS9D1-AS1 may potentially enhance carcinogenesis or may be developed as prognostic biomarkers for CRC. |
| Pubmed ID | 27895773 |
| Year | 2016 |
| Title | Dysregulation of long non-coding RNA profiles in human colorectal cancer and its association with overall survival. |
External Links
| Links for FAM83H-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |