Basic Information
| LncRNA/CircRNA Name | FAM84B-AS |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | platinum | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, etc. |
| Sample | fresh gastric cancer tissue specimens, GC cell lines (SGC-7901, MGC-803, MKN-45, AGS,HGC-27,NCIN87, BGC-823 and SGC-7901/DDP) |
| Expression Pattern | up-regulated |
| Function Description | FAM84B-AS promotes gastric cancer proliferation through inhibition of apoptosis signaling pathways and promotes drug resistance of gastric cancer cells to platinum drugs through its apoptosis-inhibiting functions. |
| Pubmed ID | 30638658 |
| Year | 2019 |
| Title | Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression. |
External Links
| Links for FAM84B-AS | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |