Basic Information
| LncRNA/CircRNA Name | FBXL19-AS1 |
| Synonyms | NA |
| Region | GRCh38_16:30919319-30923269 |
| Ensemble | ENSG00000260852 |
| Refseq | NR_024348 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR, Luciferase reporter assay etc. |
| Sample | cell lines (LoVo, HT29, HCT116, SW620) |
| Expression Pattern | up-regulated |
| Function Description | FBXL19-AS1 was the most significantly upregulated lncRNA in metastatic tumors. Our results reveal the cancer-promoting effect of FBXL19-AS1, acting as a molecular sponge in negatively modulating miR-203, which might provide a new insight for understanding of CRC development. |
| Pubmed ID | 28479250 |
| Year | 2017 |
| Title | Long non-coding RNA FBXL19-AS1 plays oncogenic role in colorectal cancer by sponging miR-203 |
External Links
| Links for FBXL19-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |