Basic Information
| LncRNA/CircRNA Name | FENDRR |
| Synonyms | NA |
| Region | GRCh38_16:86474529-86509099 |
| Ensemble | ENSG00000268388 |
| Refseq | NR_033925 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | malignant melanoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | MM tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | FENDRR mediated the metastasis phenotype of MM cells by inhibiting the expressions of MMP2 and MMP9 and antagonizing the JNK/c-Jun pathway. |
| Pubmed ID | 32134466 |
| Year | 2020 |
| Title | Long non-coding RNA FENDRR inhibits migration and invasion of cutaneous malignant melanoma cells |
External Links
| Links for FENDRR | GenBank HGNC NONCODE |
| Links for malignant melanoma | OMIM COSMIC |