Basic Information
LncRNA/CircRNA Name | AFAP1-AS1 |
Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740 |
Region | GRCh38_4:7754090-7778928 |
Ensemble | ENSG00000272620 |
Refseq | NR_026892 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot, etc. |
Sample | gastric cancer tissues, cell lines (AGS, BGC-823, MGC-803, SGC-7901) |
Expression Pattern | up-regulated |
Function Description | We found that lncRNA AFAP1-AS1 was upregulated in GC and play as an important biomarker of prognosis in GC patients. Therefore, lncRNA AFAP1-AS1 may be a biomarker for prognosis and a therapeutic target of GC. |
Pubmed ID | 28975981 |
Year | 2017 |
Title | Increased lncRNA AFAP1-AS1 expression predicts poor prognosis and promotes malignant phenotypes in gastric cancer |
External Links
Links for AFAP1-AS1 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |