Basic Information
| LncRNA/CircRNA Name | Fer1L4 |
| Synonyms | FER1L4, C20orf124 |
| Region | GRCh38_20:35558737-35607562 |
| Ensemble | ENSG00000088340 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qRT-PCR |
| Sample | renal tissue |
| Expression Pattern | up-regulated |
| Function Description | Fer1L4 lncRNA is overexpressed in ccRCC compared to adjacent normal tissues. Increased expression significantly correlates with tumor aggressiveness: high expression levels of Fer1L4 RNA were found in higher grade, higher stage, and metastatic tumors. Furthermore, Fer1L4 overexpression is an independent prognostic factor for overall, cancer-specific, and progression-free survival of patients with ccRCC. |
| Pubmed ID | 31965534 |
| Year | 2020 |
| Title | The lncRNA Fer1L4 Is an Adverse Prognostic Parameter in Clear-Cell Renal-Cell Carcinoma |
External Links
| Links for Fer1L4 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |