Basic Information
| LncRNA/CircRNA Name | FER1L4 |
| Synonyms | FER1L4, C20orf124 |
| Region | GRCh38_20:35558737-35607562 |
| Ensemble | ENSG00000088340 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | glioma tissues, cell lines (U373-MG, U251, LN-18, U87-MG and SHG-44) |
| Expression Pattern | down-regulated |
| Function Description | FER1L4 was downregulated in 91.80% of gastric cancer tissues studied.low expression of FER1L4 was associated with tumor size, histological staging, tumor infiltration depth, lymph node metastasis, distant metastasis, tumor-node-metastasis staging, angioneurotic infiltration and serum CA72-4 antigen levels.Patients that receive surgical treatment for this disease typically have a poor prognosis, particularly those with glioblastoma multiforme (GBM), for which the average survival time is <2 years.etal bovine serum (FBS), 0.25% trypsin and Dulbecco's modified Eagle's medium (DMEM) were purchased from Invitrogen. |
| Pubmed ID | 28789454 |
| Year | 2017 |
| Title | Long non-coding RNA Fer-1-like family member 4 is overexpressed in human glioblastoma and regulates the tumorigenicity of glioma cells. |
External Links
| Links for FER1L4 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |