Basic Information
| LncRNA/CircRNA Name | FEZF1-AS1 |
| Synonyms | NR_036484 |
| Region | GRCh38_7:122303658-122310077 |
| Ensemble | ENSG00000230316 |
| Refseq | NR_036484 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | GBM and non-tumor tissues, cell lines(U-251 and U-87) |
| Expression Pattern | up-regulated |
| Function Description | The overexpression of FEZF1-AS1 in GBM was further confirmed using GBM tissues from GBM patients included in this study. High levels of FEZF1-AS1 were correlated with poor survival. FEZF1-AS1 was predicted to form base pairing with miR-34a. However, overexpression of FEZF1-AS1 and miR-34a failed to affect the expression of each other. |
| Pubmed ID | 32210625 |
| Year | 2020 |
| Title | LncRNA FEZF1-AS1 Sponges miR-34a to Upregulate Notch-1 in Glioblastoma |
External Links
| Links for FEZF1-AS1 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |