Basic Information
| LncRNA/CircRNA Name | FTH1P3 |
| Synonyms | FTH1P3, FTHL3, FTHL3P |
| Region | GRCh38_2:27392784-27393367 |
| Ensemble | ENSG00000213453 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | uveal melanoma |
| ICD-0-3 | C69.9 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (OCM-1A, MUM-2C, C918, MUM-2B) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA FTH1P3 was commonly up-regulated in uveal melanoma cell lines and tissues and acted as an oncogene in uveal melanoma progression by inhibiting miR-224-5p expression. These results suggest that lncRNA FTH1P3 plays a crucial role in uveal melanoma and investigation of the underlying mechanism may be a target for the treatment of uveal melanoma. |
| Pubmed ID | 29095823 |
| Year | 2017 |
| Title | Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p |
External Links
| Links for FTH1P3 | GenBank HGNC NONCODE |
| Links for uveal melanoma | OMIM COSMIC |