Basic Information
| LncRNA/CircRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 |
| Ensemble | ENSG00000234741 |
| Refseq | NR_002578 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (Hacat, A375) |
| Expression Pattern | up-regulated |
| Function Description | Notably, compared with Hacat, A375 expressed the highest GAS5 expression level, whereas the lowest GAS5 expression was found in SK-Mel-110 cell lines. |
| Pubmed ID | 27445498 |
| Year | 2016 |
| Title | LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo. |
External Links
| Links for GAS5 | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |