Basic Information
| LncRNA/CircRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 |
| Ensemble | ENSG00000234741 |
| Refseq | NR_002578 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR etc. |
| Sample | cell lines (HEK 293T, LNCaP, W7.2c etc.) |
| Expression Pattern | down-regulated |
| Function Description | Real-time RT??CR was therefore carried out and the level of GAS5 expression was quantified in these cell lines relative to 22Rv1. 22Rv1, P4E6 and PNT2C2 cell linesexpressed similar levels of GAS5, whereas LNCaP and PC3 expressed much lower levels of GAS5. |
| Pubmed ID | 18836484 |
| Year | 2009 |
| Title | GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. |
External Links
| Links for GAS5 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |