Basic Information
| LncRNA/CircRNA Name | GOLGA2P10 |
| Synonyms | Golgin A2 pseudogene 10 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Luciferase reporter assay etc. |
| Sample | HCC tissues and adjacent non-tumor liver tissues,cell lines (MHCC-97H, QGY-7703,293T) |
| Expression Pattern | up-regulated |
| Function Description | Higher GOLGA2P10 level was correlated with shorter recurrence-free survival of HCC patients. Upon ER stress, CHOP directly bound to the promoter of GOLGA2P10 and induced its transcription via the PERK/ATF4/CHOP pathway. |
| Pubmed ID | 32332695 |
| Year | 2020 |
| Title | LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members. |
External Links
| Links for GOLGA2P10 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |