Basic Information
LncRNA/CircRNA Name | H19 |
Synonyms | NA |
Region | GRCh38_11:1995176-2001470 |
Ensemble | ENSG00000130600 |
Refseq | NR_002196 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | T cell | Survival | ||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR |
Sample | gastric tissues |
Expression Pattern | up-regulated |
Function Description | H19 is reported to be significantly upregulated in GC and its overexpression could promote cell invasiveness and increase proliferation, cell cycle progression, and depressed apoptosis |
Pubmed ID | 30945348 |
Year | 2019 |
Title | The expression profiling of circulating miR-204, miR-182, and lncRNA H19 as novel potential biomarkers for the progression of peptic ulcer to gastric cancer. |
External Links
Links for H19 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |