Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | NA |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | glioblastoma tissues |
| Expression Pattern | up-regulated |
| Function Description | H19 was consistently over-expressed in all GB patients (p < 0.001), and correlated with poorer overall survival(OS) and progression-free survival(PFS). The current GB patients were clustered by the multivariate analysis into four groups based on miR-326 and H19 expression profiles, age at diagnosis, and PFS. |
| Pubmed ID | 30096248 |
| Year | 2018 |
| Title | Long Noncoding RNA H19, and Not microRNA miR-326, Is Over-Expressed and Predicts Survival in Glioblastoma. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |