Basic Information
| LncRNA/CircRNA Name | AK021444 |
| Synonyms | POSTN, OSF-2, OSF2, PDLPOSTN, PN |
| Region | GRCh38_13:37562583-37598844 |
| Ensemble | ENSG00000133110 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | up-regulated |
| Function Description | AK021444, AK025180, and AK307796, 3 specifically up-regulated lncRNAs in metastatic lymph nodes (MLN), were confirmed to be highly expressed in MLN. The qRTPCR result was consistent with that of the microarray, in that all 3 lncRNA transcripts were differentially expressed with the same trend and reached statistical significance. |
| Pubmed ID | 26463626 |
| Year | 2015 |
| Title | Long noncoding RNA expression patterns in lymph node metastasis in colorectal cancer by microarray. |
External Links
| Links for AK021444 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |