Basic Information
| LncRNA/CircRNA Name | AB073614 |
| Synonyms | NA |
| Region | GRCh38_3:149173591-149175492 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression of AB073614 was detected in 65 glioma tissues and 13 normal brain tissues by qRT-PCR, showing that lncRNA AB073614 expression was significantly up-regulated in cancerous tissues compared with normal brain tissues, and it was positively correlated with tumor grade in glioma patients. Kaplan-Meier analysis demonstrated that increased AB073614 expression contributed to poor overall survival. Further, univariate Cox regression analysis indicated that lncRNA AB073614 overexpression was an unfavorable prognostic factor in gliomas, regardless of the tumor grade. Finally, after adjustment with age, sex, tumor grade and tumor location, multivariate Cox regression analysis suggested that both highly expressed lncRNA AB073614 and high tumor grade could be considered independent poor prognostic indicators for glioma patients |
| Pubmed ID | 27104549 |
| Year | 2016 |
| Title | Up-Regulation of Long Non-Coding RNA AB073614 Predicts a Poor Prognosis in Patients with Glioma |
External Links
| Links for AB073614 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |