Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | testicular cancer |
| ICD-0-3 | C62 |
| Methods | qPCR, ISH etc. |
| Sample | testicular tumor tissues |
| Expression Pattern | differential expression |
| Function Description | RT-PCR allowed us to detect H19 expression in three B-cell lymphomas out of four cases tested. One (case 2) remained negative, just as the bilateral spermatocytic seminomas. The expression found by RNase protection in one B cell lymphoma and one spermatocytic seminoma (not detectable using mRNA in situ hybridization) was conformed by RT-PCR. H19 expression in all other tumors showing a low, moderate or high expression using RNase protection analysis. |
| Pubmed ID | 9010236 |
| Year | 1997 |
| Title | Unique expression patterns of H19 in human testicular cancers of different etiology. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for testicular cancer | OMIM COSMIC |