Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (PK-1, AsPC-1, PK-45P, PK-45H, PK-9, PK-8, PANC-1, MIAPaCa-2, HPDE4, HPDE6), pancreas tissue |
| Expression Pattern | up-regulated |
| Function Description | H19 expression positively correlated with higher histological grades. Overexpression of H19 in PANC-1 pancreatic cancer cells induced higher motilities. |
| Pubmed ID | 29581580 |
| Year | 2018 |
| Title | Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |