Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, RNAi etc. |
| Sample | cell lines (HeLa and SiHa) |
| Expression Pattern | up-regulated |
| Function Description | H19 expression was elevated in cervical cancer cell lines and could be detected in extracellular vesicles in the culture medium. In addition, H19 promoted cell proliferation and multicellular tumor spheroid formation without significantly affecting apoptosis and cell migration. |
| Pubmed ID | 27633578 |
| Year | 2017 |
| Title | Long non-coding RNA H19 enhances cell proliferation and anchorage-independent growth of cervical cancer cell lines. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |