Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | Northern blot, ISH etc. |
| Sample | endometrial tumour tissues |
| Expression Pattern | up-regulated |
| Function Description | 34/48 carcinomas overexpressed H19 compared with the expression in normal tissues. The level of H19 expression, estimated by ISH, was highly correlated to one type of cancer, i.e. carcinomas with an epidermoid component. The level of H19 expression was also strongly correlated with tumour invasion of the reproductive organs and significantly correlated with neoplastic cell invasion of the myometrium. |
| Pubmed ID | 15618002 |
| Year | 2005 |
| Title | The human H19 gene is frequently overexpressed in myometrium and stroma during pathological endometrial proliferative events. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |