Basic Information
| LncRNA/CircRNA Name | AK023096 |
| Synonyms | PCSK5, PC5, PC6, PC6A, SPC6 |
| Region | GRCh38_9:75890644-76362339 |
| Ensemble | ENSG00000099139 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | uterine leiomyoma |
| ICD-0-3 | C57.4 |
| Methods | Microarray, qPCR, Cell proliferation assay etc. |
| Sample | uterine leiomyomas tissues, cell line (DD-HLM) |
| Expression Pattern | down-regulated |
| Function Description | AK023096 was one of top down-regulated lncRNAs in large leiomyomas, as shown in hierarchically clustered heatmap. qPCR result showed that AK023096 had a lower expression level in leiomyomas than in normal tissues in 27 of 30 cases. |
| Pubmed ID | 25268745 |
| Year | 2014 |
| Title | Integrated analysis of long noncoding RNAs and mRNAs reveals their potential roles in the pathogenesis of uterine leiomyomas. |
External Links
| Links for AK023096 | GenBank HGNC NONCODE |
| Links for uterine leiomyoma | OMIM COSMIC |