Basic Information
| LncRNA/CircRNA Name | HAGLR |
| Synonyms | HAGLR, HOXD-AS1, Mdgt |
| Region | GRCh38_2:176164051-176188958 |
| Ensemble | ENSG00000224189 |
| Refseq | NR_033979 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc. |
| Sample | non small cell lung cancer tissues, cell lines (A549, SPC-A1, NCI-H1975, NCI-H1703, and SK-MES-1) |
| Expression Pattern | up-regulated |
| Function Description | HAGLR messenger RNA of non-small cell lung cancer tissues was significantly higher. Furthermore, the expression levels of p21 and matrix metallopeptidase-9 (MMP-9) were dysregulated when HAGLR expression was suppressed. |
| Pubmed ID | 28443464 |
| Year | 2017 |
| Title | Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis |
External Links
| Links for HAGLR | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |