Basic Information
| LncRNA/CircRNA Name | HAND2-AS1 |
| Synonyms | HAND2-AS1, DEIN, NBLA00301, UPH |
| Region | GRCh38_4:173527270-173659696 |
| Ensemble | ENSG00000237125 |
| Refseq | NR_136192 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNAi, Cell proliferation assay, Cell migration assay etc. |
| Sample | cell lines (HepG2, SMMC-7721 and HCCLM9) |
| Expression Pattern | differential expression |
| Function Description | Knockdown of seven of the ten candidate lncRNAs significantly affected cell migration in at least one cell line; knockdown of three lncRNAs produced accordant alterations in cell migration in at least two cell lines by suppressing or promoting cell migration |
| Pubmed ID | 28194035 |
| Year | 2017 |
| Title | Recurrently deregulated lncRNAs in hepatocellular carcinoma. |
External Links
| Links for HAND2-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |