Basic Information
| LncRNA/CircRNA Name | HGBC |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gallbladder cancer |
| ICD-0-3 | C23.9 |
| Methods | RIP |
| Sample | GBC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that lncRNA-HGBC was upregulated in GBC and its upregulation could predict poor survival. lncRNA-HGBC promotes GBC metastasis via activation of the miR-502-3p-SET-AKT cascade, pointing to lncRNA-HGBC as a new prognostic predictor and a therapeutic target. |
| Pubmed ID | 31752906 |
| Year | 2019 |
| Title | LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis |
External Links
| Links for HGBC | GenBank HGNC NONCODE |
| Links for gallbladder cancer | OMIM COSMIC |