Basic Information
| LncRNA/CircRNA Name | HIF1A-AS1 |
| Synonyms | HIF1A-AS1, 5'aHIF-1A, 5'aHIF1alpha |
| Region | GRCh38_14:61681041-61695823 |
| Ensemble | ENSG00000258777 |
| Refseq | NR_047116 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | NSCLC tissues |
| Expression Pattern | up-regulated |
| Function Description | The levels of XIST and HIF1A-AS1 were significantly increased in tumor tissues or serum from NSCLC patients as compared to those of control group. Correlation of lncRNA-XIST or HIF1A-AS1 expression between tumor tissues and serum from the same individuals was confirmed in NSCLC patients. |
| Pubmed ID | 26339353 |
| Year | 2015 |
| Title | Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer. |
External Links
| Links for HIF1A-AS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |