Basic Information
| LncRNA/CircRNA Name | HIF2PUT |
| Synonyms | EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 |
| Region | GRCh38_2:46293667-46386703 |
| Ensemble | ENSG00000116016 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | osteosarcoma tissue,osteosarcoma stem cell lines(U2OS, MG-63, hFOB) |
| Expression Pattern | down-regulated |
| Function Description | LncRNA HIF2PUT and HIF-2a were downregulated in osteosarcoma cell lines. |
| Pubmed ID | 30966832 |
| Year | 2019 |
| Title | LncRNA HIF2PUT inhibited osteosarcoma stem cells proliferation, migration and invasion by regulating HIF2 expression. |
External Links
| Links for HIF2PUT | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |