Basic Information
| LncRNA/CircRNA Name | AK093407 |
| Synonyms | NA |
| Region | GRCh38_8:125613468-125614465 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RIP |
| Sample | osteosarcoma tissues, cell line (U-2OS) |
| Expression Pattern | up-regulated |
| Function Description | Results revealed that AK093407 was highly expressed in osteosarcoma cells and tissues. Then we demonstrated that overexpression of AK093407 promoted cell proliferation and viability and inhibited apoptosis, whereas suppression of AK093407 showed opposite effects. |
| Pubmed ID | 28469961 |
| Year | 2017 |
| Title | Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation |
External Links
| Links for AK093407 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |