Basic Information
| LncRNA/CircRNA Name | HOST2 |
| Synonyms | CERNA2, HOST2, lncRNA-HOST2 |
| Region | GRCh38_1:29554-31109 |
| Ensemble | |
| Refseq | NR_134505 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR |
| Sample | CC tissues,The normal cervical epithelial cell line (HaCaT), HPV16-positive CC cell line (CaSki and SiHa), HPV18-positive CC cell line (HeLa), and HPV-negative CC cell line (C33A) |
| Expression Pattern | up-regulated |
| Function Description | HOST2 was up-regulated but let-7b was down-regulated in HPV-positive CC tissues and cells. |
| Pubmed ID | 30964163 |
| Year | 2019 |
| Title | The expression and significance of lncRNA HOST2 and microRNA let-7b in HPV-positive cervical cancer tissues and cell lines. |
External Links
| Links for HOST2 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |