Basic Information
| LncRNA/CircRNA Name | AK123657 |
| Synonyms | NA |
| Region | GRCh38_11:17381406-17383531 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR, RNAi etc. |
| Sample | cell lines (HCT116 ,SW1116) |
| Expression Pattern | down-regulated |
| Function Description | Functional experiments demonstrated three dysregulated lncRNAs, AK123657, BX648207 and BX649059 were required for efficient invasion and proliferation suppression in CRC cell lines. |
| Pubmed ID | 24809982 |
| Year | 2014 |
| Title | A long non-coding RNA signature to improve prognosis prediction of colorectal cancer. |
External Links
| Links for AK123657 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |