Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy/apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | Eight (lincRNA-VLDLR, MEG9, H19 antisense, ncR-uPAR, NEAT1 (family), LUST, UM9-5, and HOTAIR) were significantly down-regulated in HCC tumor compared to non-tumor tissues at a significance level of. |
| Pubmed ID | 26378581 |
| Year | 2015 |
| Title | Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival. |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |