Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy0 | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-CISH etc. |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | HOTAIR, H19 and KCNQ1OT1 had significantly higher expression levels in IBC than NA, and HOTAIR and H19 were both expressed more strongly in IBC than in DCIS tissues. |
| Pubmed ID | 26323944 |
| Year | 2015 |
| Title | Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology. |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |