Basic Information
| LncRNA/CircRNA Name | HOTAIRM1 |
| Synonyms | HOXA transcript antisense RNA myeloid-specific 1 |
| Region | GRCh38_7:27095647-27100265 |
| Ensemble | ENSG00000233429 |
| Refseq | NR_038366 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | RT-qPCR, RNA-seq, Western blot |
| Sample | HK-2, ACHN and CAKI-1 cell lines |
| Expression Pattern | down-regulated |
| Function Description | the pervasive downregulation of the specific HOTAIRM1 cytoplasmic isoform HM1-3 in ccRCC and suggest possible roles of HOTAIRM1 in kidney differentiation and suppression of HIF1-dependent angiogenic pathways. |
| Pubmed ID | 31862408 |
| Year | 2020 |
| Title | HOTAIRM1 lncRNA Is Downregulated in Clear Cell Renal Cell Carcinoma and Inhibits the Hypoxia Pathway |
External Links
| Links for HOTAIRM1 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |