Basic Information
| LncRNA/CircRNA Name | HOTAIRM1 |
| Synonyms | HOTAIRM1, HOXA-AS1, HOXA1-AS1, NCRNA00179 |
| Region | GRCh38_7:27095647-27100265 |
| Ensemble | ENSG00000233429 |
| Refseq | NR_038366 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute promyelocytic leukemia |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | cell lines (NB4, HEK293) |
| Expression Pattern | up-regulated |
| Function Description | HOTAIRM1 is Highly expressed and provides a regulatory link in myeloid maturation by modulating integrin-controlled cell cycle progression at the gene expression level. |
| Pubmed ID | 24824789 |
| Year | 2014 |
| Title | Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. |
External Links
| Links for HOTAIRM1 | GenBank HGNC NONCODE |
| Links for acute promyelocytic leukemia | OMIM COSMIC |