Basic Information
| LncRNA/CircRNA Name | HOXA-AS3 |
| Synonyms | NA |
| Region | GRCh38_7:27129977-27155928 |
| Ensemble | ENSG00000254369 |
| Refseq | NR_038831 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Luciferase reporter assay, RIP, Western blot |
| Sample | HCC tumor tissues,cell lines( LO2,SMMC-7721, HepG2, Huh7,HCC-LM3 ) |
| Expression Pattern | up-regulated |
| Function Description | HOXA-AS3 is upregulated in HCC tissues and cells and related to poor overall survival rate of HCC patients |
| Pubmed ID | 30963785 |
| Year | 2019 |
| Title | LncRNA HOXA-AS3 Sponges miR-29c to Facilitate Cell Proliferation, Metastasis, and EMT Process and Activate the MEK/ERK Signaling Pathway in Hepatocellular Carcinoma. |
External Links
| Links for HOXA-AS3 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |