Basic Information
| LncRNA/CircRNA Name | ANCR |
| Synonyms | NA |
| Region | GRCh38_4:52712404-52720351 |
| Ensemble | ENSG00000226950 |
| Refseq | NR_024031 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | non small cell lung cancer tissues, cell lines (NCI-H23, NCI-H522) |
| Expression Pattern | down-regulated |
| Function Description | ANCR was significantly downregulated in NSCLC patients compared with healthy controls in lung biopsies and plasma. ANCR overexpression inhibited NSCLC cell migration and invasion. |
| Pubmed ID | 30154397 |
| Year | 2018 |
| Title | lncRA ANCR Inhibits Non-Small Cell Lung Cancer Cell Migration and Invasion by Inactivating TGF-? Pathway. |
External Links
| Links for ANCR | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |