Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | NA |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | large B-cell lymphoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | DLBCL cell lines |
| Expression Pattern | down-regulated |
| Function Description | ?-elemene significantly suppressed the viability of DLBCL cells, and ?-elemene down-regulated the lncRNA HULC expression and regulated key pro-apoptotic and anti-apoptotic proteins to induce significant apoptosis of DLBCL cells. |
| Pubmed ID | 32010942 |
| Year | 2020 |
| Title | ?-elemene suppresses tumor growth of diffuse large B-cell lymphoma through regulating lncRNA HULC-mediated apoptotic pathway |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for large B-cell lymphoma | OMIM COSMIC |