Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | HULC, HCCAT1, LINC00078, NCRNA00078 |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qPCR, Western blot, RNAi, other |
| Sample | OSCC tissues and cell lines(CAL27??SCC25??CC15??CC9) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA HULC is highly expressed in OSCC and can enhance the proliferation, migration and invasion of cancer cells and inhibit tumor cell apoptosis.Down-regulation of lncRNA HULC in SCC15 and SCC25 cells can inhibit the proliferation, migration and invasion of tumor cells and promote tumor cell apoptosis. |
| Pubmed ID | 30419657 |
| Year | 2018 |
| Title | Effect of Long Non-Coding RNA Highly Upregulated in Liver Cancer on the Biological Behavior of Oral Squamous Cell Carcinoma |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |