Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | HULC, HCCAT1, LINC00078, NCRNA00078 |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | blood (serum), cell lines (AGS, SGC-7901, MGC-803, MKN-45 etc.) |
| Expression Pattern | up-regulated |
| Function Description | HULC is upregulated in GC patients. A high serum HULC level correlated with tumor size, lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and H. pylori infection. |
| Pubmed ID | 27322075 |
| Year | 2016 |
| Title | Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer. |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |