Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | HULC, HCCAT1, LINC00078, NCRNA00078 |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, RIP, CHIP, Cells proliferation assay, etc. |
| Sample | Hep3B cell lines??uman liver cancer tissues. |
| Expression Pattern | up-regulated |
| Function Description | This study elucidates a novel mechanism that lncRNA HULC produces a vital function during hepatocarcinogenesis.HULC is negatively associated with expression of PTEN or miR15a in patients of human liver cancer. |
| Pubmed ID | 29895332 |
| Year | 2018 |
| Title | Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a. |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |