Basic Information
| LncRNA/CircRNA Name | IGF2AS |
| Synonyms | IGF2-AS, IGF2-AS1, IGF2AS, PEG8 |
| Region | GRCh38_11:2140501-2148666 |
| Ensemble | ENSG00000099869 |
| Refseq | NM_016412 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | non-small cell lung cancer tissues, cell lines (A549, H23, H226, SW900, H441, H510A, H596, SK-MES-1, H920 and H1299) |
| Expression Pattern | down-regulated |
| Function Description | IGF2AS is downregulated in both NSCLC human tumors and NSCLC cell lines, as well as in stage III or IV tumors. Downregulated IGF2AS was significantly correlated with NSCLC patients??short overall survival. |
| Pubmed ID | 28471495 |
| Year | 2017 |
| Title | Prognostic implication and functional role of long noncoding RNA IGF2AS in human non-small cell lung cancer |
External Links
| Links for IGF2AS | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |