Basic Information
| LncRNA/CircRNA Name | IRAIN |
| Synonyms | NA |
| Region | GRCh38_1:29554-31109 |
| Ensemble | |
| Refseq | NR_126453 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | multiple myeloma |
| ICD-0-3 | C42.1 |
| Methods | qPCR, Luciferase reporter assay etc |
| Sample | MM tissues, cell lines (MM.1S, U266, RPMI-8226,nPCs) |
| Expression Pattern | down-regulated |
| Function Description | IRAIN is downregulated in plasma from patients with MM and in MM cell lines. |
| Pubmed ID | 31788123 |
| Year | 2019 |
| Title | Long Noncoding RNA IRAIN Acts as Tumor Suppressor via miR-125b in Multiple Myeloma |
External Links
| Links for IRAIN | GenBank HGNC NONCODE |
| Links for multiple myeloma | OMIM COSMIC |