Basic Information
| LncRNA/CircRNA Name | LINC-ITGB1 |
| Synonyms | ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB |
| Region | GRCh38_10:32900319-33005792 |
| Ensemble | ENSG00000150093 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Western blot |
| Sample | ccRCC tissue,cell line( Caki-1, 769-P,786-O, ACHN) |
| Expression Pattern | up-regulated |
| Function Description | Linc-ITGB1 expression level in ccRCC samples was markedly higher than that of the adjacent ones. |
| Pubmed ID | 30915742 |
| Year | 2019 |
| Title | Long noncoding RNA ITGB1 promotes migration and invasion of clear cell renal cell carcinoma by downregulating Mcl-1. |
External Links
| Links for LINC-ITGB1 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |