Basic Information
| LncRNA/CircRNA Name | IUR |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR |
| Sample | PC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | In PC tissues, microRNA (miR)-200 was positively, while ZEB1 was inversely correlated with IUR. In PC cells, IUR and miR-200 overexpression mediated the downregulated ZEB1. |
| Pubmed ID | 31545930 |
| Year | 2019 |
| Title | LncRNA IUR downregulates ZEB1 by upregulating miR-200 to inhibit prostate carcinoma. |
External Links
| Links for IUR | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |