Basic Information
| LncRNA/CircRNA Name | LEF1-AS1 |
| Synonyms | NA |
| Region | GRCh38_4:108167525-108256836 |
| Ensemble | ENSG00000232021 |
| Refseq | NR_029373 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | lung cancer tissues , cell lines(H1299, A549, H1975,SPC-A-1) |
| Expression Pattern | up-regulated |
| Function Description | LEF1-AS1 upregulation in lung cancer is associated with the poor survival of patients |
| Pubmed ID | 30734202 |
| Year | 2019 |
| Title | LEF1-AS1 contributes to proliferation and invasion through regulating miR-544a/FOXP1 axis in lung cancer. |
External Links
| Links for LEF1-AS1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |