Basic Information
| LncRNA/CircRNA Name | LFAR1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | intrahepatic cholangiocarcinoma |
| ICD-0-3 | C22 |
| Methods | western blot, RT-PCR |
| Sample | ICC QBC939 cell line |
| Expression Pattern | up-regulated |
| Function Description | Targeting lnc-LFAR1 can inhibit cell proliferation, migration, invasion, and EMT by regulating the TGF?/Smad pathway to affect the occurrence and development of cholangiocarcinoma. |
| Pubmed ID | 31934072 |
| Year | 2019 |
| Title | Lnc-LFAR1 Affects Intrahepatic Cholangiocarcinoma Proliferation, Invasion, and EMT by Regulating the TGF?/Smad Signaling Pathway |
External Links
| Links for LFAR1 | GenBank HGNC NONCODE |
| Links for intrahepatic cholangiocarcinoma | OMIM COSMIC |