Basic Information
| LncRNA/CircRNA Name | LINC0000125 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | Luciferase Reporter Assay, qPCR, Western blot etc. |
| Sample | cell line U-118 MG |
| Expression Pattern | up-regulated |
| Function Description | LINC00152 knockdown significantly suppressed cells viability, migration, invasion, and induced apoptosis in vitro. LINC00152 functioned as a molecular sponge for miR-4775, and inhibition of miR-4775 reversed the tumor-suppressive effects of LINC00152 knockdown on glioma cells. |
| Pubmed ID | 28800786 |
| Year | 2046 |
| Title | Knockdown of Long Noncoding RNA LINC0000125 Suppresses Cellular Proliferation and Invasion in Glioma Cells by Regulating MiR-4775. |
External Links
| Links for LINC0000125 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |