Basic Information
| LncRNA/CircRNA Name | LINC00152 |
| Synonyms | CYTOR, C2orf59, LINC00152, NCRNA00152 |
| Region | GRCh38_2:87454781-87636740 |
| Ensemble | ENSG00000222041 |
| Refseq | NR_024204 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | tumors tissues, CRC cell line (HCT-116) |
| Expression Pattern | up-regulated |
| Function Description | A cell culture under hypoxic conditions revealed several lncRNAs,such as LINC00152, whose levels were increased in the cytoplasm of colorectal cancer cells.A database study indicated that LINC00152 shares microRNA-binding sites, such as miR-138 and miR-193, with HIF1,thus suggesting that LINC00152 could possibly function as a competing endogenous RNA that can augment Hif1 translation in the cytoplasm of hypoxic colorectal cancer cells. |
| Pubmed ID | 29345294 |
| Year | 2017 |
| Title | Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer. |
External Links
| Links for LINC00152 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |