Basic Information
| LncRNA/CircRNA Name | LINC00161 |
| Synonyms | NA |
| Region | GRCh38_21:28539318-28540355 |
| Ensemble | ENSG00000226935 |
| Refseq | NR_026552 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | 2 | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | blood, hepatocellular carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | LINC00161 was significantly upregulated in serum samples of HCC patients and showed excellent stability and specificity. LINC00161 expression was detected in serum exosome, exosome-free, and urine samples, and its levels in serum exosome were upregulated in patients with HCC as compared to controls. The levels of LINC00161 suggest a significant prediction of tumor growth and metastasis in HCC. |
| Pubmed ID | 30087703 |
| Year | 2018 |
| Title | Serum and Exosome Long Non Coding RNAs as Potential Biomarkers for Hepatocellular Carcinoma. |
External Links
| Links for LINC00161 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |